Tyrosine Hydroxylase antibody (AA 1-100)

Catalog No. ABIN8125499

This Mouse Monoclonal antibody specifically detects Tyrosine Hydroxylase in WB, IF and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Tyrosine Hydroxylase antibody (AA 1-100) (ABIN8125499)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Clone: AB2467

Product Details anti-Tyrosine Hydroxylase Antibody

Binding Specificity: AA 1-100

Purpose: Tyrosine Hydroxylase mouse mAb

Specificity: This antibody detects endogenous levels of Tyrosine Hydroxylase protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human Tyrosine Hydroxylase protein.

Isotype: IgG

Application Details

Application Notes: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine Hydroxylase

Background:

Synonyms: Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase (TH) , TH, TYH

Background: The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008],

Gene Name: TH

Protein Name: Tyrosine Hydroxylase

Gene ID: 7054

UniProt: P07101

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour