Metabotropic Glutamate Receptor 5 antibody (C-Term)

Catalog No. ABIN780390

This anti-Metabotropic Glutamate Receptor 5 antibody is a Rabbit Polyclonal antibody detecting Metabotropic Glutamate Receptor 5 in WB, IHC and ELISA. Suitable for Human.

Quick Overview for Metabotropic Glutamate Receptor 5 antibody (C-Term) (ABIN780390)

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Metabotropic Glutamate Receptor 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Metabotropic Glutamate Receptor 5 Antibody

Binding Specificity: C-Term

Specificity: Reacts with human 132 kDa protein

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): May cross react with mouse and rat due to sequence homology, do not cross react with isoform 1 of human mGluR5.

Purification: Antiserum

Immunogen: Synthetic peptide derived from Cter domain of the human mGluR5 protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/200 to 1/1000 - IHC: 1/50 to 1/200

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for Metabotropic Glutamate Receptor 5

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Alternative Name: Metabotropic Glutamate Receptor 5 (mGluR5)

Background: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity