Botulinum Neurotoxin Type A antibody (AA 1177-1195)

Catalog No. ABIN782040

Product Details anti-Botulinum Neurotoxin Type A Antibody

Target: Botulinum Neurotoxin Type A

Binding Specificity: AA 1177-1195

Reactivity: Clostridium botulinum

Host: Mouse

Clonality: Monoclonal

Conjugate: This Botulinum Neurotoxin Type A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Euglobulin precipitation

Immunogen: Synthetic peptide of C. botulinum toxin A heavy chain, a.a. 1177-1195

Clone: B29M

Isotype: IgM

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 2.8 mg/mL (OD280nm, E0.1% = 1.4)

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for Botulinum Neurotoxin Type A

Target: Botulinum Neurotoxin Type A

Abstract: Botulinum Neurotoxin Type A Products

Synonyms: bna antibody, botA antibody, botulinum neurotoxin type A antibody, atx antibody

Background: Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.Synonyms: BOTOX, BoNT/A, Bontoxilysin-A, Clostridium botulinum Toxin A

Gene ID: 1491

UniProt: P10845