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C3AR1 antibody (AA 63-8)

C3AR1 Reactivity: Rat FACS, IHC (fro) Host: Mouse Monoclonal 74 unconjugated
Catalog No. ABIN782447
  • Target See all C3AR1 Antibodies
    C3AR1 (Complement Component 3a Receptor 1 (C3AR1))
    Binding Specificity
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 63-8
    Reactivity
    • 42
    • 16
    • 9
    Rat
    Host
    • 33
    • 17
    Mouse
    Clonality
    • 32
    • 17
    • 1
    Monoclonal
    Conjugate
    • 27
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C3AR1 antibody is un-conjugated
    Application
    • 24
    • 23
    • 13
    • 13
    • 13
    • 12
    • 7
    • 7
    • 3
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This rat C3a receptor antibody detects a recombinant peptide corresponding to amino acids 161-321 of the large extracellular loop structure, which shares 34 % homology with mouse and human. Deduced amino acid sequences of human/rat C3aR is 58.5 % and 90.7 % with rat/mouse.
    Purification
    Affinity chromatography on Protein G
    Immunogen
    RBL-2H3 transfectants expressing rat C3aR Donor: BALB/c Fusion Partner: X63-Ag8.653
    Clone
    74
    Isotype
    IgG1
    Top Product
    Discover our top product C3AR1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide (NaN3) as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    C3AR1 (Complement Component 3a Receptor 1 (C3AR1))
    Abstract
    C3AR1 Products
    Synonyms
    C3AR antibody, C3a-R antibody, c3ar1 antibody, AZ3B antibody, HNFAG09 antibody, C3a anaphylatoxin chemotactic receptor antibody, complement C3a receptor 1 antibody, complement component 3a receptor 1 antibody, c3ar1 antibody, C3AR1 antibody, C3ar1 antibody
    Background
    C3aR binds to anaphylotoxin C3a which, among other things, is involved in mast cell degranulation and recruitment of immune cells to the site of inflammation. Activation of the complement cascade produces various fragments, including C3a and C5a. C3aR is characterized by seven transmembrane domains including a large extracellular loop which is coupled to a Gi protein. C3aR expression is detected on glial cells, neurons and cells belonging to the mononuclear phagocyte system. C3aR expression was shown to moderately increase after LPS stimulation.Synonyms: AZ3B, C3AR, C3AR1, C3R1, C3a anaphylatoxin chemotactic receptor, C3a-R, HNFAG09
    Gene ID
    84007
    NCBI Accession
    NP_114449
    UniProt
    O55197
    Pathways
    Complement System
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