NLRP14 antibody (N-Term)

Catalog No. ABIN783723

The Rabbit Polyclonal anti-NLRP14 antibody (ABIN783723) specifically detects NLRP14 in WB and EIA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NLRP14 antibody (N-Term) (ABIN783723)

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP14 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-NLRP14 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects NALP14 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of human NALP14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for NLRP14

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Alternative Name: NLRP14

Background: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.Synonyms: NACHT LRR and PYD domains-containing protein 14, NALP14, NOD5, Nucleotide-binding oligomerization domain protein 5

Gene ID: 338323

NCBI Accession: NP_789792

UniProt: Q86W24

Pathways: Inflammasome