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NLRP14 antibody (N-Term)
NLRP14
Reactivity: Human, Mouse, Rat
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NLRP14 Antibody
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Target
See all NLRP14 Antibodies
NLRP14
(NLR Family, Pyrin Domain Containing 14 (NLRP14))
Binding Specificity
All epitopes for NLRP14 antibodies
N-Term
Reactivity
Human, Mouse, Rat
Host
All hosts for NLRP14 antibodies
Rabbit
Clonality
All clonalities for NLRP14 antibodies
Polyclonal
Conjugate
All conjugates for NLRP14 antibodies
This NLRP14 antibody is un-conjugated
Application
All applications for NLRP14 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects NALP14 at N-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
16 amino acid peptide near the amino terminus of human NALP14
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Discover our top product NLRP14 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for NLRP14
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Target
NLRP14
(NLR Family, Pyrin Domain Containing 14 (NLRP14))
Alternative Name
NLRP14 (NLRP14 Products )
Synonyms
4921520L01Rik antibody, GC-LRR antibody, Nalp-iota antibody, Nalp14 antibody, Nalp14l antibody, NALP14 antibody, CLR11.2 antibody, NOD5 antibody, PAN8 antibody, NLR family, pyrin domain containing 14 antibody, NLR family pyrin domain containing 14 antibody, Nlrp14 antibody, NLRP14 antibody
Background
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.Synonyms: NACHT LRR and PYD domains-containing protein 14, NALP14, NOD5, Nucleotide-binding oligomerization domain protein 5
Gene ID
338323
NCBI Accession
NP_789792
UniProt
Q86W24
Pathways
Inflammasome
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