NLRP14 antibody (N-Term)

Catalog No. ABIN783723

Product Details anti-NLRP14 Antibody

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP14 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects NALP14 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of human NALP14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for NLRP14

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Alternative Name: NLRP14 (NLRP14 Products)

Synonyms: 4921520L01Rik antibody, GC-LRR antibody, Nalp-iota antibody, Nalp14 antibody, Nalp14l antibody, NALP14 antibody, CLR11.2 antibody, NOD5 antibody, PAN8 antibody, NLR family, pyrin domain containing 14 antibody, NLR family pyrin domain containing 14 antibody, Nlrp14 antibody, NLRP14 antibody

Background: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.Synonyms: NACHT LRR and PYD domains-containing protein 14, NALP14, NOD5, Nucleotide-binding oligomerization domain protein 5

Gene ID: 338323

NCBI Accession: NP_789792

UniProt: Q86W24

Pathways: Inflammasome