Annexin a1 antibody (AA 1-188)

Catalog No. ABIN783987

The Rabbit Polyclonal anti-Annexin a1 antibody (ABIN783987) specifically detects Annexin a1 in WB, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Annexin a1 antibody (AA 1-188) (ABIN783987)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Annexin a1 Antibody

Binding Specificity: AA 1-188

Specificity: Recognizes Annexin A1.
Cellular Localization: Nucleus, Cytoplasm, Cell projection, cilium, Basolateral cell membrane.

Cross-Reactivity (Details): Species reactivity (expected):Mouse (86 %), Rat (89 %), Cow (89 %), Cat (93 %)Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 188 of Human Annexin A1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C.

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: Annexin A1 / ANXA1

Background: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.Synonyms: ANX1, Annexin I, Annexin-1, Calpactin II, Chromobindin-9, LPC1, Lipocortin I, Phospholipase A2 inhibitory protein, p35

Gene ID: 301, 9606

Pathways: Hormone Transport