CNR1 antibody (AA 77-91)

Catalog No. ABIN793332

Product Details anti-CNR1 Antibody

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Binding Specificity: AA 77-91

Reactivity: Human, Rat, Mouse, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This CNR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human CNR1 / CB1. This antibody is expected to recognize both reported isoforms (NP_057167.2, NP_149421.2). Reported variants represent identical protein: NP_001153731.1, NP_001153732.1, NP_057167.2, NP_001153730.1, NP_001153698.1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Marmoset, Mouse, Rat (100%) Hamster, Elephant, Panda, Dog, Cat, Horse, Pig, Turkey, Chicken (93%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-NITEFYNKSLSSFKE from an internal region (near N-terminus) of human CNR1 / CB1 (NP_057167.2, NP_149421.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Marmoset, Mouse, Rat (100%), Hamster, Elephant, Panda, Dog, Cat, Horse, Pig, Turkey, Chicken (93%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:32000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 70+55kD bands observed in Rat Brain lysates (calculated MW of 52.9kD according to Human NP_057167.2 and 52.8kD according to Rat NP_036916.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Porcella et al, Eur J Neurosci. 2000 Mar,12(3):1123-7. PMID: 10762343). Recommended concentration: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CNR1

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Alternative Name: CNR1 / CB1 (CNR1 Products)

Synonyms: CANN6 antibody, CB-R antibody, CB1 antibody, CB1A antibody, CB1K5 antibody, CB1R antibody, CNR antibody, SKR6R antibody, cnr1-A antibody, cannabinoid receptor 1 antibody, cannabinoid receptor 1 (brain) antibody, cannabinoid receptor 1 (brain) S homeolog antibody, CNR1 antibody, Cnr1 antibody, cnr1 antibody, cnr1.S antibody

Background: Name/Gene ID: CNR1
Subfamily: Cannabinoid
Family: GPCR

Synonyms: CNR1, CB-R, CB1 receptor, CB1A, CB1R, Cannabinoid receptor 1, Cannabinoid receptor CB1, Cannabinoid Receptor I, CB1, CB1K5, CANN6, Cannabinoid receptor 1 (brain), CNR, Cannabinoid CB(1) receptor, CB1 cannabinoid receptor, Central cannabinoid receptor

Gene ID: 1268

NCBI Accession: NP_057167, NP_149421

UniProt: P21554

Pathways: Feeding Behaviour