GABBR1 antibody (pSer923) (Cy3)

Catalog No. ABIN800886

Product Details anti-GABBR1 Antibody (Cy3)

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Binding Specificity: pSer923

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABBR1 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse GABBR1 around the phosphorylation site of Ser923

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Alternative Name: Gabbr1 (GABBR1 Products)

Synonyms: GABABR1 antibody, GABBR1-3 antibody, GB1 antibody, GPRC3A antibody, dJ271M21.1.1 antibody, dJ271M21.1.2 antibody, gabbr1 antibody, GABBR1 antibody, GABA(B)R1 antibody, GABAB1 antibody, GABAbR1 antibody, bM573K1.1 antibody, gamma-aminobutyric acid type B receptor subunit 1 antibody, gamma-aminobutyric acid (GABA) B receptor, 1a antibody, gamma-aminobutyric acid (GABA) B receptor, 1 antibody, GABBR1 antibody, gabbr1a antibody, gabbr1 antibody, Gabbr1 antibody

Background:

Synonyms: GABBR1 phospho S1180, GABBR1 phospho Ser1180, p-GABBR1 Ser1180, GABAb Receptor 1, dJ271M21.1.1, dJ271M21.1.2, FLJ92613, GAB B R1, GABA B R1, GABAB R1, GABAB subunit 1c, GABAB1e, GABABR 1, GABABR1, GABB R1, GABBR 1, GABBR1 3, GABBR1, Gamma aminobutyric acid GABA B receptor 1, Gamma aminobutyric acid B receptor 1, Gamma aminobutyric acid type B receptor subunit 1, Gb 1, Gb1, GPRC 3A, GPRC3A, hGB1a, GABR1_HUMAN, Gamma-aminobutyric acid type B receptor subunit 1, GABA B Receptor 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, Seven transmembrane helix receptor.

Background: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].

Gene ID: 54393

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process