Smooth Muscle Actin antibody

Catalog No. ABIN865395

The Mouse Monoclonal anti-Smooth Muscle Actin antibody (Clone 4A4) (ABIN865395) specifically detects Smooth Muscle Actin in WB, IHC, IF, FACS and ELISA. The antibody is reactive with Human, Rat, Mouse and Monkey samples.

Quick Overview for Smooth Muscle Actin antibody (ABIN865395)

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reactivity: Human, Rat, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Smooth Muscle Actin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA

Clone: 4A4

Product Details anti-Smooth Muscle Actin Antibody

Purification: Ascitic fluid

Immunogen: Synthesized peptide of human ACTA2.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000, FC:1/200 - 1/400, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Smooth Muscle Actin

Target: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Alternative Name: ACTA2

Background: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. Synonyms: AAT6, ACTSA, -Smooth Muscle Actin

Molecular Weight: 42kDa

Gene ID: 59

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development