CDKN1C antibody

Catalog No. ABIN865500

The Mouse Monoclonal anti-CDKN1C antibody (Clone 3E3) (ABIN865500) specifically detects CDKN1C in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CDKN1C antibody (ABIN865500)

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDKN1C antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3E3

Product Details anti-CDKN1C Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CDKN1C expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CDKN1C

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Alternative Name: CDKN1C

Background: The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver. Synonyms: BWS, WBS, p57, BWCR, KIP2, CDKN1C

Molecular Weight: 57kDa

Gene ID: 1028

Pathways: Cell Division Cycle, Dopaminergic Neurogenesis