p53 antibody (N-Term)
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- Target See all p53 (TP53) Antibodies
- p53 (TP53) (Tumor Protein P53 (TP53))
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Binding Specificity
- AA 46-67, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This p53 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Anti-p53
- Specificity
- P53
- Immunogen
- Peptide derived from N-terminal sequence of human p53. Antibody recognizes the epitope between Ser46 - Pro67.
- Clone
- M26-A
- Isotype
- IgG
- Top Product
- Discover our top product TP53 Primary Antibody
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- Application Notes
- Ready to use antibody dilution. Directly use for application
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- +4˚C, Do not freeze!
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Alternative Name
- p53 (TP53 Products)
- Background
- P53 (tumor supressor protein) is general marker of cell proliferation. Its enhanced expression is in most cases related to cancer (e.g. can be used as a valuable prognostic marker of conventional renal cell carcinoma). This clone is specially produced for IHC-P applications.
- UniProt
- P04637
- Pathways
- p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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