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p53 antibody (N-Term)

The Rabbit Monoclonal anti-p53 antibody has been validated for IHC (p). It is suitable to detect p53 in samples from Human.
Catalog No. ABIN870346

Quick Overview for p53 antibody (N-Term) (ABIN870346)

Target

See all p53 (TP53) Antibodies
p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity

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Human

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This p53 antibody is un-conjugated

Application

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

M26-A
  • Binding Specificity

    • 39
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    AA 46-67, N-Term

    Purpose

    Anti-p53

    Specificity

    P53

    Immunogen

    Peptide derived from N-terminal sequence of human p53. Antibody recognizes the epitope between Ser46 - Pro67.

    Isotype

    IgG
  • Application Notes

    Ready to use antibody dilution. Directly use for application

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    +4˚C, Do not freeze!
  • Target

    p53 (TP53) (Tumor Protein P53 (TP53))

    Alternative Name

    p53

    Background

    P53 (tumor supressor protein) is general marker of cell proliferation. Its enhanced expression is in most cases related to cancer (e.g. can be used as a valuable prognostic marker of conventional renal cell carcinoma). This clone is specially produced for IHC-P applications.

    UniProt

    P04637

    Pathways

    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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