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SKA1 antibody (AA 181-255)

SKA1 Reactivity: Human ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN872640
  • Target See all SKA1 Antibodies
    SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
    Binding Specificity
    • 14
    • 5
    • 3
    • 1
    • 1
    • 1
    AA 181-255
    Reactivity
    • 25
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 25
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SKA1 antibody is un-conjugated
    Application
    • 19
    • 12
    • 12
    • 8
    • 4
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SKA1
    Isotype
    IgG
    Top Product
    Discover our top product SKA1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
    Alternative Name
    SKA1 (SKA1 Products)
    Synonyms
    C18H18orf24 antibody, C18orf24 antibody, 2810433K01Rik antibody, AV117428 antibody, RGD1310784 antibody, spindle and kinetochore associated complex subunit 1 antibody, SKA1 antibody, ska1 antibody, Ska1 antibody
    Background

    Synonyms: Ska1, SKA1_HUMAN, Spindle and kinetochore associated complex subunit 1, Spindle and kinetochore associated protein 1, Spindle and kinetochore-associated protein 1, Spindle and KT kinetochore associated 1, Spindle and KT associated 1, C18orf24, MGC10200.

    Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.

    Pathways
    M Phase
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