PDHA1 antibody (pSer293) (Alexa Fluor 350)

Catalog No. ABIN875361

Product Details anti-PDHA1 Antibody (Alexa Fluor 350)

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Binding Specificity: pSer293

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDHA1 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB)

Specificity: This phosphorylation site is homologous across the listed species. This antibody will detect PDHA2, the testis specific form, when phosphorylated at Ser293 in Human, Ser296 in Mouse, and the predicted site of Ser296 in Rat due to sequence homology.

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PDHA1 around the phosphorylation site of Ser293

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDHA1

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Alternative Name: Pdha1 (PDHA1 Products)

Synonyms: PDHA antibody, PDHCE1A antibody, PHE1A antibody, Pdha-1 antibody, pdha antibody, phe1a antibody, pdhce1a antibody, im:6895726 antibody, pdha1 antibody, wu:fd18b01 antibody, wu:fo96f03 antibody, zgc:73271 antibody, zgc:86692 antibody, Pdha1 antibody, wu:fp73b04 antibody, zgc:92705 antibody, NI36_05250 antibody, pdha1-a antibody, pdha1-b antibody, pyruvate dehydrogenase E1 alpha 1 subunit antibody, pyruvate dehydrogenase E1 alpha 1 antibody, pyruvate dehydrogenase (lipoamide) alpha 1 antibody, pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene antibody, 2-oxo acid dehydrogenase antibody, pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha antibody, pyruvate dehydrogenase alpha subunit protein antibody, pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit antibody, precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit antibody, pyruvate dehydrogenase antibody, pyruvate dehydrogenase E1 alpha 1 subunit a antibody, pyruvate dehydrogenase E1 alpha 1 subunit b antibody, pyruvate dehydrogenase E1 component subunit alpha antibody, pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog antibody, PDHA1 antibody, Pdha1 antibody, pdha1 antibody, LOC719277 antibody, VNG_RS07485 antibody, RR_RS04695 antibody, pdhA1 antibody, pdha1a antibody, pdha1b antibody, NI36_RS05240 antibody, pdha1.S antibody

Background:

Synonyms: PDHA, PDHAD, PHE1A, PDHCE1A, Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial, PDHE1-A type I, PDHA1

Background: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

Gene ID: 5160

UniProt: P08559

Pathways: Warburg Effect