EPHA2/3 antibody (pTyr588, pTyr596) (Alexa Fluor 488)

Catalog No. ABIN879951

Product Details anti-EPHA2/3 Antibody (Alexa Fluor 488)

Target: EPHA2/3 (Eph Receptor A2+A3 (EPHA2/3))

Binding Specificity: pTyr588, pTyr596

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPHA2/3 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Eph receptor A2 around the phosphorylation site of Tyr588

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EPHA2/3

Target: EPHA2/3 (Eph Receptor A2+A3 (EPHA2/3))

Alternative Name: Eph receptor A2/A3 (EPHA2/3 Products)

Background:

Synonyms: Eph receptor A2+A3 phospho Y588 + Y596 ECK, EPH Receptor A2, EPH Receptor A3, EPHA2, EPHA3, Ephrin type A receptor 2, Ephrin type A receptor 3, Epithelial cell kinase, ETK, ETK1, HEK, Tyrosine-protein kinase receptor ECK, Tyrosine-protein kinase receptor ETK1.

Background: Eph receptor A2 is the receptor for members of the ephrin-A family. It binds to ephrin-A1, -A3, -A4 and -A5. Eph receptor A3 is also a receptor for members of the ephrin-A family. It binds to ephrin-A2, -A3, -A4 and -A5 and is thought to play a role in lymphoid function. Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5. It binds more poorly to ephrin-A2 and -A3. It may play a role in a signal transduction process involved in hindbrain pattern formation.

Gene ID: 1969