APOC3 antibody (AA 41-80) (AbBy Fluor® 555)

Catalog No. ABIN883140

The AbBy Fluor® 555-conjugated Rabbit Polyclonal anti-APOC3 antibody (ABIN883140) specifically detects APOC3 in WB, IF (cc) and IF (p). The antibody is reactive with Rat samples.

Quick Overview for APOC3 antibody (AA 41-80) (AbBy Fluor® 555) (ABIN883140)

Target: APOC3 (Apolipoprotein C-III (APOC3))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC3 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-APOC3 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 41-80

Purpose: APOC3 Polyclonal Antibody, AbBy Fluor-555 Conjugated

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Apolipoprotein CIII

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for APOC3

Target: APOC3 (Apolipoprotein C-III (APOC3))

Alternative Name: APOC3

Background:

Synonyms: apo-CIII, apoC-III, Apolipoprotein C-III, Apolipoprotein C3, Apoc3

Background: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion, extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.

Gene ID: 11814

UniProt: P33622

Pathways: Carbohydrate Homeostasis, Lipid Metabolism