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Bax beta antibody (AA 141-218) (Cy3)

BAX beta Reactivity: Human FACS, IF (cc), IF (p) Host: Rabbit Polyclonal Cy3
Catalog No. ABIN884807
  • Target See all Bax beta (BAX beta) products
    Bax beta (BAX beta) (BCL2-Associated X Protein (Isoform beta) (BAX beta))
    Binding Specificity
    AA 141-218
    Reactivity
    Human
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Bax beta antibody is conjugated to Cy3
    Application
    • 13
    • 12
    • 12
    • 3
    • 3
    • 3
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Bax isoform beta
    Isotype
    IgG
  • Application Notes
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Bax beta (BAX beta) (BCL2-Associated X Protein (Isoform beta) (BAX beta))
    Abstract
    BAX beta Products
    Background

    Synonyms: Apoptosis regulator Bax cytoplasmic isoform beta, BAX, Bax B, Bax beta, BaxB, BCL2 associated X protein, BCL2 associated X protein isoform beta.

    Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].

    Gene ID
    581
    UniProt
    Q07812
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