CDCA8 antibody (AA 20-120) (HRP)

Catalog No. ABIN885411

This anti-CDCA8 antibody is a Rabbit Polyclonal antibody detecting CDCA8 in ELISA, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for CDCA8 antibody (AA 20-120) (HRP) (ABIN885411)

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA8 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CDCA8 Antibody (HRP)

Binding Specificity: AA 20-120

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Horse,Bee,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Borealin/CDCA8

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDCA8

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Alternative Name: CDCA8

Background:

Synonyms: BOR, BOREA_HUMAN, Borealin, CDCA8, Cell division cycle associated 8, Cell division cycle-associated protein 8, Dasra B, Dasra-B, DasraB, FLJ10468, FLJ12042, hDasra-B, MESRGP, OTTHUMP00000004514, Pluripotent embryonic stem cell-related gene 3 protein.

Background: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Gene ID: 55143

Pathways: Cell Division Cycle, M Phase