CCDC37 antibody (AA 201-300) (Alexa Fluor 647)

Catalog No. ABIN887658

Product Details anti-CCDC37 Antibody (Alexa Fluor 647)

Target: CCDC37 (Coiled-Coil Domain Containing 37 (CCDC37))

Binding Specificity: AA 201-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC37 antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC37

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC37

Target: CCDC37 (Coiled-Coil Domain Containing 37 (CCDC37))

Alternative Name: CCDC37 (CCDC37 Products)

Synonyms: AW048498 antibody, C030041G11Rik antibody, C230069K22Rik antibody, cilia and flagella associated protein 100 antibody, CFAP100 antibody, Cfap100 antibody

Background:

Synonyms: CCD37_HUMAN, CCDC37, Coiled-coil domain containing 37, Coiled-coil domain-containing protein 37.

Background: CCDC37 is a 611 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding CCDC37 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Gene ID: 348807