Keratin 12 (KRT12) antibody (Alexa Fluor 647)

Details for Product No. ABIN890816, Supplier: Log in to see
Antigen
  • fb05e09
  • wu:fa91b04
  • wu:fa97a07
  • wu:fb05e09
  • k12
  • xk81b2
  • K12
  • AI835216
  • Krt-12
  • Krt1-12
  • Ka12
  • keratin 91
  • keratin 12
  • keratin 12 S homeolog
  • krt91
  • KRT12
  • krt12
  • Krt12
  • krt12.S
Reactivity
Human, Mouse (Murine), Rat (Rattus)
52
22
21
2
1
Host
Rabbit
53
4
1
Clonality
Polyclonal
Conjugate
Alexa Fluor 647
5
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
38
24
19
18
12
11
3
2
1
1
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from human CK12/Cytokeratin 12
Isotype IgG
Purification Purified by Protein A.
Alternative Name CK12 (KRT12 Antibody Abstract)
Background

Cytokeratin 12 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12. Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance and intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD)

Synonyms: 65 kDa cytokeratin, CK 12, CK 3, CK12, CK3, Cytokeratin 12, Cytokeratin 3, K12, K3, keratin 12 Meesmann corneal dystrophy, Keratin 12, Keratin 3, Keratin, type I cytoskeletal 12, K1C12_HUMAN, Keratin, type II cytoskeletal 3, KRT12, KRT3.

Molecular Weight 54kDa
Gene ID 3859
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months