FAM168A antibody (AA 75-180) (Alexa Fluor 488)

Catalog No. ABIN896456

Product Details anti-FAM168A Antibody (Alexa Fluor 488)

Target: FAM168A (Family with Sequence Similarity 168, Member A (FAM168A))

Binding Specificity: AA 75-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM168A antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM168A/TCRP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM168A

Target: FAM168A (Family with Sequence Similarity 168, Member A (FAM168A))

Alternative Name: TCRP1 (FAM168A Products)

Synonyms: KIAA0280 antibody, TCRP1 antibody, 2610030B18Rik antibody, B930006L02Rik antibody, mKIAA0280 antibody, family with sequence similarity 168 member A antibody, family with sequence similarity 168, member A antibody, FAM168A antibody, Fam168a antibody

Background:

Synonyms: F168A_HUMAN, Fam168a, KIAA0280, Protein FAM168A, TCRP1, Tongue cancer chemotherapy resistance-associated protein 1.

Background: FAM168A is a 244 amino acid protein that exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11, which makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.