IRX3 antibody (AA 401-501) (HRP)

Catalog No. ABIN903095

Product Details anti-IRX3 Antibody (HRP)

Target: IRX3 (Iroquois Homeobox 3 (IRX3))

Binding Specificity: AA 401-501

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRX3 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Iroquois homeobox protein 3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IRX3

Target: IRX3 (Iroquois Homeobox 3 (IRX3))

Alternative Name: Iroquois homeobox protein 3 (IRX3 Products)

Synonyms: IRX-1 antibody, IRXB1 antibody, AI894186 antibody, iro3 antibody, irx3b antibody, xiro-3 antibody, xiro3 antibody, hm:zehn0543 antibody, id:ibd3380 antibody, irx3 antibody, wu:fk88a03 antibody, zgc:109805 antibody, wu:fb36a07 antibody, zgc:76885 antibody, ziro3b antibody, iroquois homeobox 3 antibody, Iroquois related homeobox 3 antibody, iroquois homeobox 3 L homeolog antibody, iroquois homeobox 3a antibody, iroquois homeobox 3b antibody, IRX3 antibody, Irx3 antibody, irx3.L antibody, irx3a antibody, irx3b antibody

Background:

Synonyms: IRX-1, IRXB1, Iroquois-class homeodomain protein IRX-3, Homeodomain protein IRXB1, Iroquois homeobox protein 3, IRX3, IRX3_HUMAN

Background: Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).

Gene ID: 79191

UniProt: P78415

Pathways: Tube Formation