PLEKHM3 antibody (AA 651-761) (Alexa Fluor 350)

Catalog No. ABIN911437

Product Details anti-PLEKHM3 Antibody (Alexa Fluor 350)

Target: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Binding Specificity: AA 651-761

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHM3 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLEKHM3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PLEKHM3

Target: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Alternative Name: PLEKHM3 (PLEKHM3 Products)

Synonyms: PLEKHM1L antibody, DAPR antibody, 9430067K14Rik antibody, A230102O09Rik antibody, AI449570 antibody, Plekhm1l antibody, Dapr antibody, RGD1307151 antibody, pleckstrin homology domain containing, family M, member 3 antibody, pleckstrin homology domain containing M3 antibody, pleckstrin homology domain containing M3 L homeolog antibody, PLEKHM3 antibody, Plekhm3 antibody, plekhm3.L antibody

Background:

Synonyms: DAPR, PH domain containing family M member 3, PH domain-containing family M member 3, PKHM3_HUMAN, Pleckstrin homology domain containing family M member 3, Pleckstrin homology domain-containing family M member 3, PLEKHM1L, Plekhm3.

Background: PLEKHM3 (pleckstrin homology domain containing, family M, member 3), also known as DAPR or PLEKHM1L (pleckstrin homology domain containing, family M, member 1-like), is a 761 amino acid phosphoprotein that contains two pleckstrin homology (PH) domains and one phorbol-ester/DAG-type zinc finger. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PLEKHM3 exists as three alternatively spliced isoforms that participate in metal ion binding. The gene that encodes PLEKHM3 maps to human chromosome 2q33.3. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.