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PLK1 antibody (AA 201-300) (AbBy Fluor® 350)

This Rabbit Polyclonal antibody specifically detects PLK1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.
Catalog No. ABIN911479

Quick Overview for PLK1 antibody (AA 201-300) (AbBy Fluor® 350) (ABIN911479)

Target

See all PLK1 Antibodies
PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivity

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Human

Host

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  • 33
  • 2
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Rabbit

Clonality

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Polyclonal

Conjugate

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This PLK1 antibody is conjugated to AbBy Fluor® 350

Application

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Binding Specificity

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    AA 201-300

    Cross-Reactivity

    Human

    Predicted Reactivity

    Mouse,Rat,Dog,Pig,Rabbit

    Purification

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human PLK1

    Isotype

    IgG
  • Application Notes

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    PLK1 (Polo-Like Kinase 1 (PLK1))

    Alternative Name

    PLK1

    Background

    Synonyms: PLK, STPK13, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, PLK1

    Background: PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.

    Gene ID

    5347

    UniProt

    P53350

    Pathways

    Cell Division Cycle, M Phase
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