Rab3a+Rab3b+Rab3c+Rab3d (AA 101-150) antibody (Alexa Fluor 555)

Catalog No. ABIN912708

Product Details

Target: Rab3a+Rab3b+Rab3c+Rab3d

Binding Specificity: AA 101-150

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Rab3A+Rab3B+Rab3C+Rab3D

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Rab3a+Rab3b+Rab3c+Rab3d

Background:

Synonyms: RAB3A, RAB3A member RAS oncogene family, RAB3B, RAB3B member RAS oncogene family, RAB3C, RAB3C member RAS oncogene family, RAB3D member RAS oncogene family, RAD3D, Ras related protein Rab 3A, Ras related protein Rab 3B, Ras related protein Rab 3C, Ras related protein Rab 3D, D2 2, Glioblastoma overexpressed, GOV, RAB16.

Background: Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has four known isoforms: 3A, 3B, 3C and 3D. These proteins are expressed in the highest concentration in the brain and endocrine tissues and are involved in regulated exocytosis of hormones and neurotransmitters. Specifically Rab3's are thought to play a role in presynaptic vesicle trafficking and priming.