RETNLB antibody (AA 24-80) (Alexa Fluor 488)

Catalog No. ABIN913364

Product Details anti-RETNLB Antibody (Alexa Fluor 488)

Target: RETNLB (Resistin Like beta (RETNLB))

Binding Specificity: AA 24-80

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RETNLB antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RELM beta/CCGR

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RETNLB

Target: RETNLB (Resistin Like beta (RETNLB))

Alternative Name: RELM beta (RETNLB Products)

Synonyms: FIZZ1 antibody, FIZZ2 antibody, HXCP2 antibody, RELM-beta antibody, RELMb antibody, RELMbeta antibody, XCP2 antibody, RETNLB antibody, 9030012B21Rik antibody, Fizz2 antibody, Relmb antibody, Xcp3 antibody, resistin like beta antibody, RETNLB antibody, Retnlb antibody

Background:

Synonyms: Resistin like protein beta, C/EBP epsilon regulated myeloid specic secreted cysteine rich protein precursor 2, CCGR, Colon and small intestine specic cysteine rich protein, Colon and small intestine-specic cysteine-rich protein, Colon carcinoma related gene protein, Colon carcinoma-related gene protein, Cysteine rich secreted A12 alpha like protein 1, Cysteine rich secreted protein A12 alpha like 1, Cysteine rich secreted protein FIZZ2, Cysteine-rich secreted protein A12-alpha-like 1, Cysteine-rich secreted protein FIZZ2, FIZZ1, FIZZ2, Found in inflammatory zone 1, Found in Inflammatory Zone 2, HXCP2, RELM beta, RELMb, RELMbeta, Resistin like beta, Resistin Like Protein Beta, Resistin-like beta, RETNB_HUMAN, RETNL2. RETNLB, XCP2.

Background: The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin, also known as ADSF) is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.

Gene ID: 84666

Pathways: Hormone Activity