VPS4B antibody (N-Term)

Catalog No. ABIN926774

The Rabbit Polyclonal anti-VPS4B antibody has been validated for WB. It is suitable to detect VPS4B in samples from Human.

Quick Overview for VPS4B antibody (N-Term) (ABIN926774)

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS4B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VPS4B Antibody

Binding Specificity: N-Term

Purification: Purified

Immunogen: VPS4 B antibody was raised in rabbit using the N terminal of VPS4 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

VPS4B Blocking Peptide, catalog no. 33R-10320, is also available for use as a blocking control in assays to test for specificity of this VPS4B antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for VPS4B

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Alternative Name: VPS4B

Background: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16. Synonyms: Polyclonal VPS4B antibody, Anti-VPS4B antibody, vacuolar protein sorting 4 homolog B, S. cerevisiae antibody, MIG1 antibody, SKD1 antibody, SKD1B antibody, VPS4-2 antibody.

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events