IGF1R antibody (Middle Region)
-
- Target See all IGF1R Antibodies
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Chicken, Pig, Xenopus laevis
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This IGF1R antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus), Pig (Porcine), Cow (Bovine), Chicken, Zebrafish (Brachydanio rerio), Frog
- Purification
- Purified
- Immunogen
- IGF1 R antibody was raised in rabbit using the middle region of IGF1 as the immunogen
- Top Product
- Discover our top product IGF1R Primary Antibody
-
-
- Application Notes
-
WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
-
IGF1R Blocking Peptide, catalog no. 33R-2144, is also available for use as a blocking control in assays to test for specificity of this IGF1R antibody
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
-
- Target
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- Alternative Name
- IGF1R (IGF1R Products)
- Synonyms
- CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody
- Background
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Synonyms: Polyclonal IGF1R antibody, Anti-IGF1R antibody, insulin-like growth factor 1 receptor antibody, CD221 antibody, IGFIR antibody, JTK13 antibody, MGC142170 antibody, MGC142172 antibody, MGC18216 antibody.
- Pathways
- RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
-