TRAF4 antibody (Middle Region)

Catalog No. ABIN926937

Product Details anti-TRAF4 Antibody

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF4 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Zebrafish (Brachydanio rerio), Frog, Dog (Canine)

Purification: Purified

Immunogen: TRAF4 antibody was raised in rabbit using the middle region of TRAF4 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TRAF4 Blocking Peptide, catalog no. 33R-4877, is also available for use as a blocking control in assays to test for specificity of this TRAF4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Alternative Name: TRAF4 (TRAF4 Products)

Synonyms: CART1 antibody, MLN62 antibody, RNF83 antibody, A530032M13Rik antibody, msp2 antibody, traf4 antibody, cart1 antibody, mln62 antibody, rnf83 antibody, traf-4 antibody, traf4l antibody, zgc:77418 antibody, TNF receptor associated factor 4 antibody, Tnf receptor associated factor 4 antibody, tnf receptor-associated factor 4b antibody, TNF receptor associated factor 4 L homeolog antibody, tnf receptor-associated factor 4a antibody, TRAF4 antibody, Traf4 antibody, traf4b antibody, traf4.L antibody, traf4a antibody

Background: TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Synonyms: Polyclonal TRAF4 antibody, Anti-TRAF4 antibody, TNF receptor-associated factor 4 antibody, CART1 antibody, MLN62 antibody, RNF83 antibody.