VEGFR2/CD309 antibody (N-Term)

Catalog No. ABIN926995

This Rabbit Polyclonal antibody specifically detects VEGFR2/CD309 in WB and IHC. It exhibits reactivity toward Human and Dog.

Quick Overview for VEGFR2/CD309 antibody (N-Term) (ABIN926995)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VEGFR2/CD309 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-VEGFR2/CD309 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Dog (Canine)

Purification: Purified

Immunogen: KDR antibody was raised in rabbit using the N terminal of KDR as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

KDR Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this KDR antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name: KDR

Background: KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Synonyms: Polyclonal KDR antibody, Anti-KDR antibody, kinase insert domain receptor, a type III receptor tyrosine kinase antibody, CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody.

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling