TLE1 antibody (N-Term)
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- Target See all TLE1 Antibodies
- TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Zebrafish (Danio rerio), Chicken
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TLE1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Chicken, Zebrafish (Brachydanio rerio)
- Purification
- Purified
- Immunogen
- TLE1 antibody was raised in rabbit using the N terminal of TLE1 as the immunogen
- Top Product
- Discover our top product TLE1 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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TLE1 Blocking Peptide, catalog no. 33R-8077, is also available for use as a blocking control in assays to test for specificity of this TLE1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
- Alternative Name
- TLE1 (TLE1 Products)
- Synonyms
- ESG antibody, ESG1 antibody, GRG1 antibody, C230057C06Rik antibody, Estm14 antibody, Grg1 antibody, Tle4l antibody, TLE1 antibody, transducin like enhancer of split 1 antibody, transducin-like enhancer protein 1 antibody, transducin-like enhancer of split 1 antibody, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antibody, TLE1 antibody, Smp_150080 antibody, Tle1 antibody, LOC100354911 antibody, LOC100524475 antibody, LOC100061341 antibody
- Background
- TLE1 is a transcriptional corepressor that binds to a number of transcription factors. TLE1 inhibits NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE1 has an unusual function as coactivator for ESRRG. Synonyms: Polyclonal TLE1 antibody, Anti-TLE1 antibody, transducin-like enhancer of split 1, E, sp1 homolog, Drosophila antibody, ESG antibody, ESG1 antibody, GRG1 antibody.
- Pathways
- WNT Signaling, SARS-CoV-2 Protein Interactome
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