AIM2 antibody (N-Term)

Catalog No. ABIN928372

This Rabbit Polyclonal antibody specifically detects AIM2 in WB. It exhibits reactivity toward Human, Mouse, Rat and Zebrafish (Danio rerio).

Quick Overview for AIM2 antibody (N-Term) (ABIN928372)

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AIM2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: AIM2 antibody was raised in rabbit using the N terminal of AIM2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

AIM2 Blocking Peptide, (ABIN938120), is also available for use as a blocking control in assays to test for specificity of this AIM2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for AIM2

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Alternative Name: AIM2

Background: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. Synonyms: Polyclonal AIM2 antibody, Anti-AIM2 antibody, absent in melanoma 2 antibody, PYHIN4 antibody.

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome