Importin 5 antibody (N-Term)

Catalog No. ABIN928690

Product Details anti-Importin 5 Antibody

Target: Importin 5 (IPO5)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Importin 5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: RANBP5 antibody was raised in rabbit using the N terminal of RANBP5 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RANBP5 Blocking Peptide, catalog no. 33R-3453, is also available for use as a blocking control in assays to test for specificity of this RANBP5 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Importin 5

Target: Importin 5 (IPO5)

Alternative Name: RANBP5 (IPO5 Products)

Synonyms: IPO5 antibody, RANBP5 antibody, IMB3 antibody, KPNB3 antibody, Pse1 antibody, imp5 antibody, 1110011C18Rik antibody, 5730478E03Rik antibody, AA409333 antibody, C76941 antibody, Kpnb3 antibody, Ranbp5 antibody, importin 5 antibody, IPO5 antibody, Ipo5 antibody

Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Synonyms: Polyclonal RANBP5 antibody, Anti-RANBP5 antibody, importin 5 antibody, DKFZp686O1576 antibody, FLJ43041 antibody, IMB3 antibody, KPNB3 antibody, MGC2068 antibody, RANBP5 antibody.

Pathways: Protein targeting to Nucleus