IL-5 antibody (Middle Region)

Catalog No. ABIN928720

This Rabbit Polyclonal antibody specifically detects IL-5 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for IL-5 antibody (Middle Region) (ABIN928720)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL-5 Antibody

Binding Specificity: Middle Region

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Il5 antibody was raised in rabbit using the middle region of Il5 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Il5 Blocking Peptide, (ABIN5614177), is also available for use as a blocking control in assays to test for specificity of this Il5 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: Il5

Background: The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony  stimulating factor 2 (CSF2/GM-CSF). Synonyms: Polyclonal Il5 antibody, Anti-Il5 antibody, interleukin 5 antibody, Il-5 antibody.

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour