alpha Adaptin antibody (C-Term)

Catalog No. ABIN929410

This Rabbit Polyclonal antibody specifically detects alpha Adaptin in WB. It exhibits reactivity toward Human.

Quick Overview for alpha Adaptin antibody (C-Term) (ABIN929410)

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Adaptin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-alpha Adaptin Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: AP2 A1 antibody was raised in rabbit using the C terminal of AP2 1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

AP2A1 Blocking Peptide, (ABIN5612095), is also available for use as a blocking control in assays to test for specificity of this AP2A1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for alpha Adaptin

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Alternative Name: AP2A1

Background: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. Synonyms: Polyclonal AP2A1 antibody, Anti-AP2A1 antibody, adaptor-related protein complex 2, alpha 1 subunit antibody, ADTAA antibody, AP2-ALPHA antibody, CLAPA1 antibody.

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation