ATF2 antibody

Catalog No. ABIN930912

The Mouse Monoclonal anti-ATF2 antibody (Clone ATF25I062) (ABIN930912) specifically detects ATF2 in IP and DB. The antibody is reactive with Human samples.

Quick Overview for ATF2 antibody (ABIN930912)

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATF2 antibody is un-conjugated

Application: Immunoprecipitation (IP), Dot Blot (DB)

Clone: ATF25I062

Product Details anti-ATF2 Antibody

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogen: ATF2 antibody was raised in mouse using recombinant Activating Transcription Factor 2 (Atf2)

Isotype: IgG1

Application Details

Application Notes: WB: 0.2-2 µg/mL, IP: 100-500 µg/sample
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: ATF2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Target Details for ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Alternative Name: ATF2

Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. Synonyms: Monoclonal ATF2 antibody, Anti-ATF2 antibody, Activating transcription factor 2 antibody, HB16 antibody, CREB2 antibody, TREB7 antibody, CRE-BP1 antibody, MGC111558 antibody.

Pathways: MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades