KIT antibody

Catalog No. ABIN931449

The Mouse Monoclonal anti-KIT antibody (Clone 8D7) (ABIN931449) specifically detects KIT in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for KIT antibody (ABIN931449)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KIT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 8D7

Product Details anti-KIT Antibody

Immunogen: c-Kit antibody was raised in Mouse using a purified recombinant fragment of C-kit expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: C-Kit

Background: Proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117 is a protein that in humans is encoded by the KIT gene. Multiple transcript variants encoding different isoforms have been found for this gene. CD117 is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. This receptor binds to stem cell factor (a substance that causes certain types of cells to grow). Altered forms of this receptor may be associated with some types of cancer. Synonyms: Monoclonal c-Kit antibody, Anti-c-Kit antibody, C-kit antibody, CD117 antibody, cd117 antigen antibody, mast/stem cell growth factor receptor antibody, protein kinase kit antibody, Proto-oncogene tyrosine-protein kinase Kit antibody, receptor tyrosine kinase kit antibody, scfr antibody, v-kit antibody.

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity