Integrin beta 2 antibody

Catalog No. ABIN933062

The Mouse Monoclonal anti-Integrin beta 2 antibody has been validated for ELISA and IF. It is suitable to detect Integrin beta 2 in samples from Human and Mouse.

Quick Overview for Integrin beta 2 antibody (ABIN933062)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Clone: 1E13

Product Details anti-Integrin beta 2 Antibody

Cross-Reactivity: Mouse (Murine)

Immunogen: CD18 antibody was raised in Mouse using a purified recombinant fragment of CD18 expressed in E. coli as the immunogen.

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:10,000, IF: 1:200-1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Background: Integrins are receptors that mediate attachment between a cell and the tissues surrounding it, which may be other cells or the extracellular matrix (ECM). They also play a role in cell signaling and thereby regulate cellular shape, motility, and the cell cycle. Integrins work alongside other proteins such as cadherins, Immunoglobulin superfamily cell adhesion molecules, selectins and syndecans to mediate cell-cell and cell-matrix interaction and communication. Synonyms: Monoclonal CD18 antibody, Anti-CD18 antibody, Cluster of differentiation 18 antibody, b2 Integrin antibody, beta 2 Integrin antibody.

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation