CDK7 antibody (C-Term)

Catalog No. ABIN933264

The Mouse Monoclonal anti-CDK7 antibody (Clone Mo-1-1) (ABIN933264) specifically detects CDK7 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for CDK7 antibody (C-Term) (ABIN933264)

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: Mo-1-1

Product Details anti-CDK7 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine)

Purification: Protein A affinity chromatography

Immunogen: Cdk7 antibody was raised in mouse using recombinant C-terminal 221 aa fragment of human wild-type cdk7/CAK (cyclin activating kinase) as the immunogen.

Isotype: IgG2b

Application Details

Application Notes: IHC: 1:10 - 1:20
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in distilled water, final solution contains 0.09 % sodium azide, 0.5 % BSA in PBS buffer, pH 7.4

Concentration: Lot specific

Buffer: Supplied in lyophilized form.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for CDK7

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Alternative Name: Cdk7

Background: Cell division protein kinase 7 is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). Synonyms: Cyclin dependent kinase 7 antibody, Monoclonal Cdk7 antibody, Anti Cdk7 antibody, Monoclonal Cdk Activating Kinase antibody, Anti Cdk Activating Kinase antibody.

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase