IL12 antibody

Catalog No. ABIN933784

This Rat Monoclonal antibody specifically detects IL12 in ELISA, WB and Inhibition. It exhibits reactivity toward Mouse.

Quick Overview for IL12 antibody (ABIN933784)

Target: IL12 (Interleukin 12 (IL12))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL12 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Blocking Antibody (Inhibition)

Clone: M912296

Product Details anti-IL12 Antibody

Immunogen: IL12 antibody was raised in rat using highly pure recombinant Mouse IL-12 as the immunogen.

Isotype: IgG1 kappa

Application Details

Application Notes: ELISA: 4-8 µg/mL, Inhibition: 0.16-0.24 µg/mL, WB: 2-4 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for IL12

Target: IL12 (Interleukin 12 (IL12))

Alternative Name: IL12

Background: IL12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells. Synonyms: Monoclonal IL12 antibody, Anti-IL12 antibody, IL-12 antibody, Interleukin 12 antibody, NKSF antibody, CTL maturation factor antibody, TCMF antibody, Cytotoxic lymphocyte maturation factor antibody, CLMF antibody, TSF antibody.

Molecular Weight: 75 kDa (predicted detection band MW)

Pathways: JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome