TNF alpha antibody (HRP)

Catalog No. ABIN933922

This Mouse Monoclonal antibody specifically detects TNF alpha in ELISA. It exhibits reactivity toward Human.

Quick Overview for TNF alpha antibody (HRP) (ABIN933922)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is conjugated to HRP

Application: ELISA

Clone: KT31

Product Details anti-TNF alpha Antibody (HRP)

Purification: Protein A affinity chromatography

Immunogen: TNF alpha antibody was raised in Mouse using recombinant human TNF alpha as the immunogen.

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:1000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in PBS containing 0.1 % sodium azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF alpha

Background: Tumor necrosis factor (TNF) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. The primary role of TNF is in the regulation of immune cells. TNF is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Synonyms: Monoclonal TNF alpha antibody, Anti-TNF alpha antibody, TNF-alpha antibody, TNFa antibody, TNF-a antibody, Tumor Necrosis Factor antibody, TNFSF2 antibody, Cachectin antibody, Differentiation-inducing factor antibody, DIF antibody, Necrosin antibody, Cytotoxin antibody.

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome