Complement Factor B antibody
Quick Overview for Complement Factor B antibody (ABIN933984)
Target
See all Complement Factor B (CFB) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- Protein G affinity chromatography
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Immunogen
- Factor B antibody was raised in Mouse using purified Factor B from human blood as the immunogen.
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Isotype
- IgG2b
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Application Notes
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ELISA: 5 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Supplied in PBS containing 0.1 % sodium azide as a preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- -20 °C/-80 °C
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Storage Comment
- Store at 4 °C for up to 1 month. For long term storage, aliquot and store at -20 to -80 °C.
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- Complement Factor B (CFB)
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Alternative Name
- Factor B
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Background
- Factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. It is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 ug/mL. In the presence of Mg++ factor B binds to C3b and the C3b,B complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease. Synonyms: Monoclonal Factor B antibody, Anti-Factor B antibody, Factor-B antibody, Complement factor B antibody.
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Pathways
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
Target
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