CD25 antibody

Catalog No. ABIN933997

This Rat Monoclonal antibody specifically detects CD25 in FACS, IP and Inhibition. It exhibits reactivity toward Mouse.

Quick Overview for CD25 antibody (ABIN933997)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD25 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Antibody (Inhibition)

Clone: 3C7

Product Details anti-CD25 Antibody

Immunogen: CD25 antibody (Azide free) was raised in rat using alpha chain IL-2 receptor as the immunogen.

Isotype: IgG2b

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in PBS.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: CD25

Background: CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression. Synonyms: Monoclonal CD25 antibody, Anti-CD25 antibody, CD25 IL2-R alpha TAC antibodyIL2-R alpha TAC antibody, IL2Ra antibody.

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation