NGFB antibody

Catalog No. ABIN934073

Product Details anti-NGFB Antibody

Target: NGFB (Nerve Growth Factor beta (NGFB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NGFB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Boric acid precipitation/S-Sepharose. Source: Ascites

Immunogen: beta NGF antibody was raised in mouse using highly pure recombinant human beta-NGF as the immunogen.

Clone: M912261

Isotype: IgG2b kappa

Application Details

Application Notes: ELISA: 2-4 µg/mL, Inhibition: 2.7-4 µg/mL, WB: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for NGFB

Target: NGFB (Nerve Growth Factor beta (NGFB))

Alternative Name: beta NGF (NGFB Products)

Synonyms: NGFB antibody, ngfb antibody, ns:zft386 antibody, xx:zft386 antibody, zgc:109730 antibody, hsan5 antibody, beta-ngf antibody, Ngfb antibody, Beta-NGF antibody, HSAN5 antibody, beta-NGF antibody, nerve growth factor antibody, nerve growth factor b (beta polypeptide) antibody, beta-Nerve growth factor antibody, nerve growth factor (beta polypeptide) antibody, NGF antibody, ngfb antibody, FPV072 antibody, FPV076 antibody, ngf antibody, Ngf antibody

Background: Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. Synonyms: Monoclonal beta NGF antibody, Anti-beta NGF antibody, beta-NGF antibody, NGF-beta antibody, Nerve Growth factor antibody.

Pathways: NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size