SLC3A2 antibody (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2)

Details for Product anti-SLC3A2 Antibody No. ABIN94255
Antigen
Reactivity
Human
223
50
23
Host
Mouse
137
101
7
5
Clonality (Clone)
Monoclonal ()
Conjugate
This SLC3A2 antibody is un-conjugated
24
21
16
7
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
147
81
66
55
46
33
32
13
12
10
6
5
1
Options
Immunogen RAJI human Burkitt's lymphoma cell line
Clone MEM-108
Isotype IgG1
Specificity The antibody MEM-108 reacts with CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells, it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.
HLDA VI, WS Code BP 409
HLDA VI, WS Code NL N-L017
Cross-Reactivity (Details) Human
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Antigen
Alternative Name CD98 (SLC3A2 Antibody Abstract)
Background CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Supplier Images
Image no. 1 for anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody (ABIN94255) Surface staining of human peripheral blood monocytes with anti-human CD98 (MEM-108) p...