SLC3A2 antibody (Biotin)

Catalog No. ABIN94256

The Mouse Monoclonal anti-SLC3A2 antibody is suitable to detect SLC3A2 in samples from Human. It has been validated for FACS, IP and IHC (p).

Quick Overview for SLC3A2 antibody (Biotin) (ABIN94256)

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC3A2 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MEM-108

Product Details anti-SLC3A2 Antibody (Biotin)

Purpose: Anti-Hu CD98 Biotin

Cross-Reactivity (Details): Human

Characteristics: The antibody MEM-108 reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells, it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.

Purification: Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Immunogen: RAJI human Burkitt's lymphoma cell line

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 3 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for SLC3A2

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Alternative Name: CD98

Background: Solute carrier family 7 member 5,CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.,4F2, MDU1, 4F2HC, 4T2HC, NACAE, SLC3A2

Gene ID: 8140

UniProt: Q01650