HSD17B1 antibody (C-Term)

Catalog No. ABIN950180

The Rabbit Polyclonal anti-HSD17B1 antibody has been validated for WB and EIA. It is suitable to detect HSD17B1 in samples from Human.

Quick Overview for HSD17B1 antibody (C-Term) (ABIN950180)

Target: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HSD17B1 Antibody

Binding Specificity: AA 226-256, C-Term

Specificity: This antibody recognizes Human 17-beta-HSD1 / HSD17B1 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 226-256 amino acids from the C-terminal region of human 17-beta-HSD1 / HSD17B1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HSD17B1

Target: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Alternative Name: 17-beta-HSD1 / HSD17B1

Background: Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.Synonyms: 17-beta-hydroxysteroid dehydrogenase type 1, 17E2DH, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha HSD, E17KSR, EDH17B1, EDH17B2, EDHB17, Estradiol 17-beta-dehydrogenase 1, Placental 17-beta-hydroxysteroid dehydrogenase

Molecular Weight: 34950 Da

Gene ID: 3292

NCBI Accession: NP_000404

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis