ANGPTL4 antibody (Middle Region)

Catalog No. ABIN950414

The Rabbit Polyclonal anti-ANGPTL4 antibody is suitable to detect ANGPTL4 in samples from Human and Mouse. It has been validated for WB, IHC (p) and EIA.

Quick Overview for ANGPTL4 antibody (Middle Region) (ABIN950414)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ANGPTL4 Antibody

Binding Specificity: AA 145-175, Middle Region

Specificity: This antibody reacts to ANGPTL4.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 145~175 amino acids from the Center region of human ANGPTL4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Alternative Name: ANGPTL4 / FIAF

Background: ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.Synonyms: ARP4, Angiopoietin-like 4, Angiopoietin-related protein 4, Fasting-induced adipose factor, HFARP, Hepatic fibrinogen/angiopoietin-related protein, PGAR

Gene ID: 51129

NCBI Accession: NP_001034756

Pathways: Regulation of Lipid Metabolism by PPARalpha