ACCN4 antibody (N-Term)

Catalog No. ABIN950537

Product Details anti-ACCN4 Antibody

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Binding Specificity: AA 22-52, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to ASIC4 / ACCN4.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 22-52 amino acids from the N-terminal region of human ACCN4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ACCN4

Target: ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))

Alternative Name: ASIC4 / ACCN4 (ACCN4 Products)

Synonyms: ACCN4 antibody, BNAC4 antibody, Accn4 antibody, Spasic antibody, acid sensing ion channel subunit family member 4 S homeolog antibody, acid sensing ion channel subunit family member 4 antibody, acid-sensing (proton-gated) ion channel family member 4 antibody, asic4.S antibody, ASIC4 antibody, Asic4 antibody

Background: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.Synonyms: Acid-sensing ion channel 4, Amiloride-sensitive cation channel 4

Gene ID: 55515

NCBI Accession: NP_061144