Cardiac Troponin T2 antibody (Middle Region)
Quick Overview for Cardiac Troponin T2 antibody (Middle Region) (ABIN951043)
Target
See all Cardiac Troponin T2 (cTnT) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 171-201, Middle Region
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Specificity
- This antibody detects Cardiac Troponin T (Center).
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse
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Purification
- Protein A column followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 171-201 amino acids from the Central region of human TNNT2
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))
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Alternative Name
- Cardiac Troponin T
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Background
- The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.Synonyms: TNNT2, TnTc, cTnT
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Gene ID
- 7139
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NCBI Accession
- NP_000355
Target
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