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Endothelin 1 antibody (C-Term)
EDN1
Reactivity: Human
WB, IF, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Endothelin 1 Antibody
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Target
See all Endothelin 1 (EDN1) Antibodies
Endothelin 1 (EDN1)
Binding Specificity
All epitopes for Endothelin 1 antibodies
AA 183-211, C-Term
Reactivity
All reactivities for Endothelin 1 antibodies
Human
Host
All hosts for Endothelin 1 antibodies
Rabbit
Clonality
All clonalities for Endothelin 1 antibodies
Polyclonal
Conjugate
All conjugates for Endothelin 1 antibodies
This Endothelin 1 antibody is un-conjugated
Application
All applications for Endothelin 1 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human Endothelin-1 (C-term). Other species not tested.
Purification
Affinity Chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of human EDN1
Isotype
Ig Fraction
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Discover our top product EDN1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Endothelin 1
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Target
Endothelin 1 (EDN1)
Alternative Name
Endothelin-1 (EDN1 Products )
Synonyms
et1 antibody, et-1 antibody, Edn1 antibody, EDN antibody, ET-1 antibody, ET1 antibody, PPET1 antibody, HDLCQ7 antibody, preproET antibody, Et1 antibody, fb14d01 antibody, wu:fb14d01 antibody, PPET-1 antibody, EDN1 antibody, edn1 antibody, edn1-a antibody, edn1-b antibody, endothelin 1 antibody, endothelin 1 S homeolog antibody, endothelin 1 L homeolog antibody, edn1 antibody, EDN1 antibody, Edn1 antibody, edn1.S antibody, edn1.L antibody
Background
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: EDN1, ET1, HDLCQ7, PPET1, Preproendothelin-1
Molecular Weight
24425 Da
Gene ID
1906
NCBI Accession
NP_001161791
Pathways
Hormone Transport , Negative Regulation of Hormone Secretion , Regulation of Systemic Arterial Blood Pressure by Hormones , cAMP Metabolic Process , Regulation of Muscle Cell Differentiation , Regulation of G-Protein Coupled Receptor Protein Signaling , Regulation of Cell Size
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